Collagen XII Interacts with Avian Tenascin-X through Its NC3 Domain
نویسندگان
چکیده
منابع مشابه
Tenascin-X, collagen, elastin, and the Ehlers-Danlos syndrome.
Tenascin-X is an extracellular matrix protein initially identified because the gene encoding it overlaps with the human CYP21B gene. Because studies of gene and protein function of other tenascins had been poorly predictive of essential functions in vivo, we used a genetic approach that critically relied on an understanding of the genomic locus to uncover an association between inactivating ten...
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The adaptor protein STAC3 is essential for skeletal muscle excitation-contraction (EC) coupling and a mutation in the STAC3 gene has been linked to a severe muscle disease, Native American myopathy (NAM). However the function of STAC3, its interaction partner, and the mode of interaction within the EC-coupling complex remained elusive. Here we demonstrate that STAC3 forms a stable interaction w...
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A monoclonal antibody specific for the chicken alpha 1 (XII) collagen chain was used to immunolocalize type XII collagen in the corneoscleral of 17-19-day-old chicken embryos. These immunofluorescence studies localized type XII collagen around the scleral cartilages and ossicles. There was also a striking positive staining in the scleral spur and stroma of the corneolimbus beneath the external ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2006
ISSN: 0021-9258
DOI: 10.1074/jbc.m603147200